Frequency of Hyperinsulinism at Liaquat University Hospital

// January 14th, 2011 // My Publications, Research

ABSTRACT:

OBJECTIVE: To determine the frequency of hyperinsulinism at Liaquat University Hospital, Jamshoro

STUDY DESIGN: Prospective analytical study.

PLACE AND DURATION: Department of Plastic & Reconstructive surgery and outdoor patient Department, Liaquat University Hospital, Jamshoro Pakistan from January 2008to January 2009.

PATIENTS AND METHODS: Fifty consecutive cases of hirsuitism diagnosed on the basis of Ferriman Gallway score of > 8 from age 15-45 years, fasting insulin levels werechecked along with blood pressure, fasting blood sugar, body mass index and waistcircumference. The patients of age more than 45 years and fasting blood sugar of morethan 125 mg/dl were excluded from this study.RESULTS: 25 (50%) out of 50 hirsutes were found with hyperinsulinism, mean fastinginsulin level 20.3680 SD± 3.71637  μu/ml. The hirsute patients with and withouthyperinsulinism were compared on the basis of fasting insulin level, BMI, blood pressure,fasting blood sugar and waist circumference. Their p-values were calculated and foundsignificant for fasting insulin level and fasting blood sugar.

CONCLUSION: Hirsutes are more prone for development of diabetes mellitus type 2 infuture due to hyperinsulinism and insulin resistance and needs proper surveillance.

Medical Channel: Oct-Dec 2010. Vol. 16, No. 4; 574-77

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